Treatment is individualized balancing clinical efficacy and unwanted adverse effects. It is essential to consult with your treating physician to consider appropriate treatment. Medications for Parkinson’s disease can be separated into those predominately for the motoric and non-motoric symptoms.

Below is a list of medications commonly prescribed for Parkinson’s Disease.

Motor

  • Carbidopa/Levodopa
  • Dopamine agonists
  • MAO-B inhibitors
  • COMT-Inhibitors
  • Amantadine
  • Anticholinergies

 

Autonomic Dysfunction

  • Constipation – dietary change, stool softeners, laxatives
  • Orthostatic hypotension – mineralocorticoid, pressors, norepinephrine prodrug
  • Sialorrhea – botulinum toxin, anticholinergics

Psychiatric

  • Dementia – acetylcholinesterase inhibitors
  • Depression – serotonin reuptake inhibitor, serotonin norepinephrine reuptake inhibitors
  • Psychosis – atypical antipsychotics
  • REM sleep behavior disorder – benzodiazepine, melatonin